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Last Updated: 01/25/17

Available Agents

Click on column header to sort by Agent Name, Company or Agent Class

Agent Name NSC Number Company Agent Class Agent Target/Molecular Target(s)
Alectinib 794611 Genentech ALK inhibitor, tyrosine kinase inhibitor ALK, RET
Atezolizumab 783608 Genentech PD-L1 blocking monoclonal antibody PD-L1
Bevacizumab 704865 Genentech Anti-angiogenesis inhibitor, monoclonal antibody VEGF
Cobimetinib 781257 Genentech MEK1/2 inhibitor MEK1/2
Ensartinib 784729 Xcovery Holding Company LLC ALK inhibitor ALK, TrkA, TrkC, ROS, EphA2, c-MET
Ipilimumab 732442 Bristol-Myers Squibb anti-CTLA-4 monoclonal anibody CTLA-4
Larotrectinib 788607 Loxo Oncology Tyrosine kinase inhibitor NTRK-1, NTRK-2, NTRK-3 fusion proteins; TrkA/B/C proteins
LY3039478   Eli Lilly and Company Notch inhibitor Notch
Mogamulizumab 791064 Kyowa Hakko Kirin Co., Ltd. anti-CCR4 monoclonal antibody CC chemokine receptor 4 (CCR4)-expressing cells
Nivolumab 748726 Bristol-Myers Squibb PD-1 blocking monoclonal antibody PD-1
Obinutuzumab 793436 Genentech anti-CD20 monoclonal antibody CD20
Pertuzumab 740102 Genentech anti-HER2 monoclonal antibody HER2/neu
Prexasertib   Eli Lilly and Company Checkpoint kinase 1 inhibitor CHK1
Trastuzumab 688097 Genentech anti-HER2 monoclonal antibody HER2/neu
Vemurafenib 761431 Genentech BRAF mutant v600 inhibitor BRAF V600 mutant, CRAF, ARAF, wild-type BRAF, SRMS, ACK1, MAP4K5, FGR
Vismodegib 747691 Genentech Hedgehog Inhibitor Smoothened