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Last Updated: 10/30/17

Available Agents

Click on column header to sort by Agent Name, Company or Agent Class

Agent Name NSC Number Company Agent Class Agent Target/Molecular Target(s)
Alectinib 794611 Genentech ALK inhibitor, tyrosine kinase inhibitor ALK, RET
Atezolizumab 783608 Genentech PD-L1 blocking monoclonal antibody PD-L1
AZD1775 751084 AstraZeneca WEE1 kinase inhibitor WEE1
AZD5069   AstraZeneca CXCR2 antagonist CXCR2
AZD5363 782347 AstraZeneca serine/threonine kinase (AKT) inhibitor AKT 1, AKT 2, AKT 3
AZD6738   AstraZeneca ATR kinase inhibitor ATR
Bevacizumab 704865 Genentech Anti-angiogenesis inhibitor, monoclonal antibody VEGF
Blinatumomab 765986 Amgen Inc Bispecific T-cell engager (BiTE) monoclonal antibody CD3, CD19
Cediranib 732208 AstraZeneca VEGF RTK inhibitor VEGFR-1, VEGFR-2, VEGFR-3, c-Kit
Cobimetinib 781257 Genentech MEK1/2 inhibitor MEK1/2
Durvalumab 778709 AstraZeneca PD-L1 blocking monoclonal antibody PD-L1, CD80
Ensartinib 784729 Xcovery Holding Company LLC ALK inhibitor ALK, TrkA, TrkC, ROS, EphA2, c-MET
Ipilimumab 732442 Bristol-Myers Squibb anti-CTLA-4 monoclonal anibody CTLA-4
Larotrectinib 788607 Loxo Oncology Tyrosine kinase inhibitor NTRK-1, NTRK-2, NTRK-3 fusion proteins; TrkA/B/C proteins
Mogamulizumab 791064 Kyowa Hakko Kirin Co., Ltd. anti-CCR4 monoclonal antibody CC chemokine receptor 4 (CCR4)-expressing cells
Nivolumab 748726 Bristol-Myers Squibb PD-1 blocking monoclonal antibody PD-1
Obinutuzumab 793436 Genentech anti-CD20 monoclonal antibody CD20
Olaparib 747856 AstraZeneca PARP inhibitor PARP-1, PARP-2, PARP-3
Pertuzumab 740102 Genentech anti-HER2 monoclonal antibody HER2/neu
Prexasertib   Eli Lilly and Company Checkpoint kinase 1 inhibitor CHK1
Savolitinib 785348 AstraZeneca MET kinase inhibitor MET
Talimogene laherparepvec 785349 Amgen Inc Genetically modified oncolytic virus  
Trastuzumab 688097 Genentech anti-HER2 monoclonal antibody HER2/neu
Tremelimumab 744483 AstraZeneca anti-CTLA-4 monoclonal anibody CTLA-4
Vemurafenib 761431 Genentech BRAF mutant v600 inhibitor BRAF V600 mutant, CRAF, ARAF, wild-type BRAF, SRMS, ACK1, MAP4K5, FGR
Vismodegib 747691 Genentech Hedgehog Inhibitor Smoothened