Available Agents

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Agent Name	NSC Number	Company	Agent Class	Agent Target/Molecular Target(s)
Alectinib	794611	Genentech	ALK inhibitor, tyrosine kinase inhibitor	ALK, RET
Atezolizumab	783608	Genentech	PD-L1 blocking monoclonal antibody	PD-L1
Avelumab	799232	EMD Serono, Inc.	PD-L1 Inhibitor	PD-L1
Bevacizumab	704865	Genentech	Anti-angiogenesis inhibitor, monoclonal antibody	VEGF
Blinatumomab	765986	Amgen Inc	Bispecific T-cell engager (BiTE) monoclonal antibody	CD3, CD19
Capivasertib	782347	AstraZeneca	serine/threonine kinase (AKT) inhibitor	AKT 1, AKT 2, AKT 3
Ceralasertib	802785	AstraZeneca	ATR kinase inhibitor	ATR
Cobimetinib	781257	Genentech	MEK1/2 inhibitor	MEK1/2
Durvalumab	778709	AstraZeneca	PD-L1 blocking monoclonal antibody	PD-L1, CD80
Ensartinib	784729	Xcovery Holding Company LLC	ALK inhibitor	ALK, TrkA, TrkC, ROS, EphA2, c-MET
Giredestrant	840836	Genentech	Selective estrogen receptor degrader (SERD)	ER-targeting therapy
Glofitamab	845088	Genentech	Bispecific monoclonal antibody	CD20 expressed on the surface of B cells and CD3 receptor expressed on the surface of T cells.
Inavolisib	843575	Genentech	Class I PI3Kα	Class I PI3Kα isoform (p110α)
Ipilimumab	732442	Bristol-Myers Squibb	anti-CTLA-4 monoclonal anibody	CTLA-4
Larotrectinib	788607	Bayer	Tyrosine kinase inhibitor	NTRK-1, NTRK-2, NTRK-3 gene fusions; TrkA/B/C fusion proteins
Mirdametinib		SpringWorks Therapeutics, Inc.	MEK1/2 inhibitor	MEK1, MEK2
Mogamulizumab	791064	Kyowa Hakko Kirin Co., Ltd.	anti-CCR4 monoclonal antibody	CC chemokine receptor 4 (CCR4)-expressing cells
Nirogacestat	811402	SpringWorks Therapeutics, Inc.	Gamma Secretase Inhibitor	Gamma Secretase
Nivolumab	748726	Bristol-Myers Squibb	PD-1 blocking monoclonal antibody	PD-1
Obinutuzumab	793436	Genentech	anti-CD20 monoclonal antibody	CD20
Olaparib	747856	AstraZeneca	PARP inhibitor	PARP-1, PARP-2, PARP-3
Pertuzumab	740102	Genentech	anti-HER2 monoclonal antibody	HER2/neu
Pertuzumab/trastuzumab/ hyaluronidase-zzxf	827796	Genentech	Fully human immunoglobulin monoclonal antibodies	Human epidermal growth factor receptor 2 (HER2, also known as c-erbB-2)
Regorafenib	821745	Bayer	L01XE21	VEGFR1, VEGFR2, VEGFR3, TIE2, PDGFRB, FGFR1, KIT, RET, RAF1, BRAF
Savolitinib	785348	AstraZeneca	MET kinase inhibitor	MET
SX-682		Syntrix Biosystems, Inc.	CXCR1 and CXCR2 inhibitor	CXCR1 and CXCR2 expressing cells
Talimogene laherparepvec	785349	Amgen Inc	Genetically modified oncolytic virus
Tiragolumab	827799	Genentech	Fully human immunoglobulin monoclonal antibody	T-Cells and natural killer (NK) cell subsets
Trastuzumab	688097	Genentech	anti-HER2 monoclonal antibody	HER2/neu
Trastuzumab and hyaluronidase-oysk	827797	Genentech	Fully human immunoglobulin monoclonal antibody	Human epidermal growth factor receptor 2 (HER2, also known as c-erbB-2)
Tremelimumab	744483	AstraZeneca	anti-CTLA-4 monoclonal anibody	CTLA-4