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Last Updated: 04/06/20

Available Agents

Click on column header to sort by Agent Name, Company or Agent Class

Agent Name NSC Number Company Agent Class Agent Target/Molecular Target(s)
Alectinib 794611 Genentech ALK inhibitor, tyrosine kinase inhibitor ALK, RET
Atezolizumab 783608 Genentech PD-L1 blocking monoclonal antibody PD-L1
Avelumab 799232 EMD Serono, Inc. PD-L1 Inhibitor PD-L1
AZD1775 751084 AstraZeneca WEE1 kinase inhibitor WEE1
AZD5069 812793 AstraZeneca CXCR2 antagonist CXCR2
AZD5363 782347 AstraZeneca serine/threonine kinase (AKT) inhibitor AKT 1, AKT 2, AKT 3
AZD6738 802785 AstraZeneca ATR kinase inhibitor ATR
AZD8186 785347 AstraZeneca PI3K inhibitor PI3K beta/delta
Bevacizumab 704865 Genentech Anti-angiogenesis inhibitor,  monoclonal antibody VEGF
Blinatumomab 765986 Amgen Inc Bispecific T-cell engager (BiTE) monoclonal antibody CD3, CD19
Cediranib 732208 AstraZeneca VEGF RTK inhibitor  VEGFR-1, VEGFR-2, VEGFR-3, c-Kit
Cobimetinib 781257 Genentech MEK1/2 inhibitor MEK1/2
Durvalumab 778709 AstraZeneca PD-L1 blocking monoclonal antibody PD-L1, CD80
Ensartinib 784729 Xcovery Holding Company LLC ALK inhibitor ALK, TrkA, TrkC, ROS, EphA2, c-MET
Ipilimumab 732442 Bristol-Myers Squibb anti-CTLA-4 monoclonal anibody CTLA-4
Larotrectinib 788607 Bayer Tyrosine kinase inhibitor NTRK-1, NTRK-2, NTRK-3 gene fusions; TrkA/B/C fusion proteins
Mogamulizumab 791064 Kyowa Hakko Kirin Co., Ltd. anti-CCR4 monoclonal antibody CC chemokine receptor 4 (CCR4)-expressing cells
Nivolumab 748726 Bristol-Myers Squibb PD-1 blocking monoclonal antibody PD-1
Obinutuzumab 793436 Genentech anti-CD20 monoclonal antibody CD20
Olaparib 747856 AstraZeneca PARP inhibitor PARP-1, PARP-2, PARP-3
Pertuzumab 740102 Genentech anti-HER2 monoclonal antibody HER2/neu
Regorafenib 821745 Bayer L01XE21 VEGFR1, VEGFR2, VEGFR3, TIE2, PDGFRB, FGFR1, KIT, RET, RAF1, BRAF 
Savolitinib 785348 AstraZeneca MET kinase inhibitor MET
Selpercatinib 812076 Eli Lilly and Compnay Selective RET Inhibitor RET
SX-682   Syntrix Biosystems, Inc. CXCR1 and CXCR2 inhibitor CXCR1 and CXCR2 expressing cells
Talimogene laherparepvec 785349 Amgen Inc Genetically modified oncolytic virus  
Trastuzumab 688097 Genentech anti-HER2 monoclonal antibody HER2/neu
Tremelimumab 744483 AstraZeneca anti-CTLA-4 monoclonal anibody CTLA-4
Vemurafenib 761431 Genentech BRAF mutant v600 inhibitor BRAF V600 mutant, CRAF, ARAF, wild-type BRAF, SRMS, ACK1, MAP4K5, FGR  
Vismodegib 747691 Genentech Hedgehog Inhibitor Smoothened
Vistusertib 787289 AstraZeneca mTOR kinase inhibitor mTOR kinase